Developing therapies to fight Obesity

Developing therapies to fight Obesity

Developing therapies to fight Obesity

It is really a good news for people suffering from obesity or figure conscious people. Although still more work is needed but work done so far is very exciting.

As we all know fat has a bad reputation. But for scientists fat is one of the most fascinating tissue and we are only now beginning to understand fat. In short there are two types by which our body stores fat, white fat is bad fat causing bulges and brown fat is good fat which can be used by body for energy needs. White fat is the fat stored in body and is not used for energy (tummy fat) while brown fat is used up when energy is required by body like when exposed to cold weather etc.

The white fat predisposes one to diabetes and heart problem. This is also one of the reasons why different group of people react to fat rich diet. In some all the fat is converted to white fat and stored and in some it is converted in brown fat which is used when body requires energy.

In brief this is the reason why some gain weight and some not when on almost similar diet.

Another recent study revealed that exercising causes brown fat to be created from regular white fat.

Browning’ white fat helps treat obesity

In recent studies, scientists have found that lean people tend to have more brown fat than overweight people and that when stimulated it can burn calories. Scientists are eyeing it as a potential obesity treatment if they can figure out a way to increase a person’s brown fat. It’s known that children have more brown fat than adults and brown fat stores decline in adults.

Although leaner adults have more brown fat than heavier people, even their brown fat cells are greatly outnumbered by white fat cells. A 150-pound person might have 20 or 30 pounds of fat. They are only going to have 2 or 3 ounces of brown fat. But that 2 ounces, if maximally stimulated, could burn off 300 to 500 calories a day.

In future one would require only a pill to eat all the tasty pizzas, french fries without bulging tummy. You might give people a drug that increases brown fat,

By manipulating the metabolic pathways in the body responsible for converting vitamin A, retinol, into retinoic acid, a team of researchers have discovered a way to turn foe to friend by essentially making white fat take on characteristics of brown fat. Brown seems to be the colour of choice when it comes to the types of fat cells in our bodies. Brown fat expends energy, while its counterpart, white fat stores it.

The danger in white fat cells, along with the increased risk for diabetes and heart disease it poses, seems especially linked to visceral fat. Visceral fat is the build-up of fat around the organs in the belly. So in the battle against obesity, brown fat appears to be our friend and white fat our foe.

“Brown fat, and mechanisms that might allow white fat to take on brown fat characteristics, has been receiving increasing attention as a possible way to treat obesity and its complications,” Plutzky said.

For more information visit us HealthFore Technologies Limited is a global healthcare IT solutions and advisory services company. Our patient-centric healthcare solutions focus on wellness, preventive care and condition management. Our information and health advisory services ensure prompt diagnosis and treatment of diseases. We create mass awareness to improve the quality of life through self-care.


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